拱形的力量科学报告:VIM Gene

来源：百度文库编辑：偶看新闻时间：2024/05/05 19:06:36

Entrez Gene summary for VIM:

This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and

actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell

shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune

response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site

of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration,

and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract

Entrez Gene summary for FN1:
This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or

multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and

migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis.

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